Making sure those defectors don't destroy the very cooperative systems they're abusing is an age-old problem, and we've developed a variety of societal pressures to induce cooperation: moral systems, reputational systems, institutional systems, and security systems.
Understanding how these different societal pressures work — and fail — is essential to understanding the problems we face in today's increasingly technological and interconnected world.
Here's Bruce Schneier's keynote from Hack in The Box Amsterdam 2012:
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